Proposals (S2S)

Frequently Asked Questions

• Can I bulk load users and profiles as an Admin?
• Can I copy and transform proposals?
• How do I manage permissions as an Admin?
• How do I input proposal information?
• How do I manage Org Units as an Admin?
• I'm having trouble adding a Key Person

Release Notes

• May 11, 2026 - Proposals (S2S) Release Notes
• April 1, 2026 - Proposals (S2S) Patch Notes
• March 17, 2026 - Proposals (S2S) Release Notes
• February 10, 2026 - Proposals (S2S) Release Notes
• August 28, 2025 - Proposals (S2S) Patch Notes
• August 25, 2025 - Proposals (S2S) Release Notes

General Resources

• Am I Platform-enabled?
• Troubleshooting Submission Errors in Proposals S2S
• Subawards.com User Guide
• Cayuse Proposals S2S VPAT
• Using Your Cayuse 424 Training Environment
• Authorizing Cayuse 424 with Grants.gov

All Roles: Opportunities

• Downloading Opportunities in Cayuse Proposals (S2S)
• Viewing Opportunity Information in Cayuse Proposals (S2S)
• Searching for Opportunities in Proposals (S2S)
• Administrators: Removing Opportunities
• Distinguishing Between Opportunities with the Same Number in Cayuse Proposals (S2S)
• Downloading Opportunities into Cayuse Proposals (S2S) Training Environments

Proposals

• Sensitive Language Detector
• Using the NIH Validations Service in Proposals (S2S)
• Understanding Agency vs. Sponsor in Proposals (S2S)
• Creating a New Proposal in Proposals (S2S)
• Searching for Proposals in Proposals (S2S)
• Changing Your Proposal Title in Proposals (S2S)

Multi-Project Proposals

• Importing and Exporting Multi-Project Components in Proposals (S2S)
• Creating New Linked Components in Proposals (S2S)
• Linking an Existing Component in Proposals (S2S)

Subawards

• Creating Subawards in Proposals (S2S)
• Linking to a Prime in Proposals (S2S)
• Linking Subawards in Proposals (S2S)
• Unlinking from a Prime in Proposals (S2S)
• Importing Subawards in Proposals (S2S)
• Exporting Subawards in Proposals (S2S)

Routing

• Creating Routing Profiles in Proposals (S2S)
• Editing Routing Chains in Proposals (S2S)
• Starting the Routing Process in Proposals (S2S)
• Approving or Rejecting Proposals in Proposals (S2S)
• Submitting a Proposal in Proposals (S2S)

Attachments

• Uploading Attachments in Proposals (S2S)
• Appending Attachments in Proposals (S2S)
• Uploading Implodable Attachments for the PHS Research Training Program Form in Proposals (S2S)
• Uploading Explodable/Composite Attachments in Proposals (S2S)
• Adding Attachments Further Down the Numbered List in Proposals (S2S)
• Complying with Grants.gov and Agency PDF Requirements

Budget

• Editing the Budget Period in Proposals (S2S)
• Overwriting Calculated Fields in Proposals (S2S)
• Escalating and Replicating Rates in Proposals (S2S)
• Understanding the NIH Salary Cap in Proposals (S2S)

Key Persons

• (Platform-enabled only) Adding Local Person
• Adding Key Persons in Proposals (S2S)
• Accessing Key Person Budget Entries in Proposals (S2S)
• Troubleshooting: Adding Key Persons in Proposals (S2S)
• Adding a Fastlane ID to an NSF Proposal
• Pulling Information for Professional Profiles in Proposals (S2S)

Fund Finder

• Configuring Cayuse Proposals (S2S) Integration for Pivot

Administrators: Reports

• Managing System-Wide Reporting in Proposals (S2S)
• Viewing Proposal Agency Tracking Numbers in Proposals (S2S)

System Administrators: The Admin Module (Platform-enabled customers)

• What is the Admin Module?

Administrators: User Management

• Creating a Profile and Connecting a User Account in Proposals (S2S)
• Deleting a Profile in Proposals (S2S)
• Searching for and Editing a Profile in Proposals (S2S)
• Managing General Personal Information in Proposals (S2S)
• Managing Permissions in Proposals (S2S)
• Managing User Access in Proposals (S2S)

Proposals S2S Administration

• Administrators: System Setup
• Administrators: Internal Organizations (Institutions)

Agency

• CDMRP
• NIH
• NSF